Multitask Dyadic Prediction and Its Application in Prediction of Adverse Drug-Drug Interaction

Authors: Bo Jin, Haoyu Yang, Cao Xiao, Ping Zhang, Xiaopeng Wei, Fei Wang

AAAI 2017 | Conference PDF | Archive PDF | Plain Text | LLM Run Details

Reproducibility Variable Result LLM Response
Research Type Experimental Evaluation on real world datasets is presented to demonstrate the effectiveness of the proposed approach.
Researcher Affiliation Collaboration Computer Science, Dalian University of Technology, Dalian, China 116024 *Health Analytics Research Group, IBM T.J.Watson Research Center, Yorktown Heights, NY 10598 Healthcare Policy and Research, Weill Cornell Medical College, Cornell University, New York, NY 10065
Pseudocode Yes Algorithm 1 Alternating PGD algorithm; Algorithm 2 Accelerated PGD for O with fixed P and Q
Open Source Code No The paper does not provide a concrete access link or explicit statement about the availability of the source code for the methodology.
Open Datasets Yes The DDI data we used in evaluation is extracted from FDA Adverse Event Reporting System (FAERS)1. [...] Mined from FAERS, the Twosides database2 (Tatonetti et al. 2012) is a resource of polypharmacy side effects for pairs of drugs. [...] 1https://open.fda.gov/data/faers/; 2http://tatonettilab.org/resources/tatonetti-stm.html
Dataset Splits Yes To be specific, we randomly selected a fixed percentage (10%) of drugs for testing, and considered all DDIs associated with these drugs as testing set. Then we constructed the models with the remaining DDIs as the training set. The model parameters were tuned with cross validation based on the training set.
Hardware Specification No The paper does not provide specific hardware details (e.g., CPU/GPU models, memory) used for running its experiments.
Software Dependencies No The paper does not provide specific software dependencies with version numbers needed to replicate the experiment.
Experiment Setup No The paper does not provide specific experimental setup details, such as hyperparameter values or training configurations.